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Chimpanzee vs bonobo table11/23/2023 ![]() We examined the peptide binding ability of all 219 different MHC class I molecules to 5,788,712 peptides derived from 1432 different primate viruses and analyzed the percentage of bound peptides and the overlap of the peptide binding repertoires of the two species. Here, we use a bioinformatic approach to analyze the viral peptide binding ability of all published bonobo MHC class I molecules ( n = 58) in comparison to all published chimpanzee MHC class I molecules ( n = 161) for the class I loci A, B, C and A-like. Although several studies found reduced MHC class I diversity in bonobos in comparison to the closely related chimpanzee, it is unclear if this lower diversity also influences the functional ability of MHC class I molecules in bonobos. The bonobo genome compared with the chimpanzee and human genomes – Nature.The highly polymorphic genes of the major histocompatibility complex (MHC) class I are involved in defense against viruses and other intracellular pathogens. R., Walenz, B., Koren, S., Sutton, G., Kodira, C.
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